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Chroma vs io.github.cyanheads/chembl-mcp-server

Chroma is an MCP server published by chroma-core. Marketplaces we read that list it: 1 (Docker MCP Catalog). io.github.cyanheads/chembl-mcp-server is an MCP server published by cyanheads. Marketplaces we read that list it: 1 (Official MCP Registry). As of our marketplace pass on 2026-10-18. This pair was picked by a reader, not by our comparison rule, so search engines are asked not to index the page.

Where each is published

Where each is published
MarketplaceChromaio.github.cyanheads/chembl-mcp-server
Docker MCP Catalog Listed
Version: sha256:c050ca8e1d4e
Forks (GitHub): 117
Pulls (Docker Hub): 60 198
Stars (Docker Hub): 5
Stars (GitHub): 600
Not marked · First seen
Not listed
Official MCP Registry Not listed Listed
Version: 0.4.0
Downloads/month (npm): 1 215
Downloads/week (npm): 344
Forks (GitHub): 0
Stars (GitHub): 1
Not marked · First seen

Each figure is the marketplace's own and is never added up across marketplaces. A marketplace that publishes no figure shows none: no number is not zero.

The facts side by side

Chroma vs io.github.cyanheads/chembl-mcp-server
FactChromaio.github.cyanheads/chembl-mcp-server
Marketplaces that list it11
Stars (GitHub) (differs)600 (better)1 (worse)
Pulls (Docker Hub) (differs)60 198No figure on Docker Hub
Forks (GitHub) (differs)117 (better)0 (worse)
Last release (differs)Not published2026-10-18
Where it runs (differs)On your machine (mcp/chroma)Remote server (chembl.caseyjhand.com/mcp)
Transport (differs)stdioStreamable HTTP
Tools it declares (differs)13Not published
Environment variables it asks for (differs)1, secrets among them: 115, secrets among them: 0
Licence (differs)Apache-2.0Not stated
Repository (differs)github.com/chroma-core/chroma-mcpgithub.com/cyanheads/chembl-mcp-server
Changes in the last 7 days (differs)02
First seen2026-10-112026-10-11
Endpoint at the last check (differs)no remote endpoint we checkResponded 29 h ago

Lines where the two differ have a tinted background and bold values. Where the data itself says which value is better (more marketplaces, a larger figure of the same marketplace, a fresher release, a verified mark on a marketplace that lists both), the better one is also marked green with ▲ and the worse one red with ▼. Where it runs, the transport, the tools, the settings, hooks, the bundle's parts, the licence and the week's changes are marked only as different: more or fewer is not better in itself.

What each says it does

Chroma

In its own words, on Docker MCP Catalog:

A Model Context Protocol (MCP) server implementation that provides database capabilities for Chroma.

io.github.cyanheads/chembl-mcp-server

In its own words, on Official MCP Registry:

Link compounds to protein targets, rank bioactivity, and look up drug mechanisms and indications.

How to run each

Chroma As a local MCP server: Docker image

Claude Code
claude mcp add --env "CHROMA_API_KEY=<YOUR_CHROMA_API_KEY>" --transport stdio chroma -- docker run -i --rm -e CHROMA_API_KEY mcp/chroma

Requires: CHROMA_API_KEY (secret)

io.github.cyanheads/chembl-mcp-server As a remote MCP server

Claude Code
claude mcp add --transport http chembl-mcp-server https://chembl.caseyjhand.com/mcp

Commands built only from what the marketplaces declare; the full set for every client is on each card.

Only io.github.cyanheads/chembl-mcp-server has a remote endpoint we check. How we check endpoints

Tools each declares

The marketplaces of io.github.cyanheads/chembl-mcp-server publish no list of tools, so we do not compare tools.

Settings each asks for

Only Chroma asks for

  • CHROMA_API_KEY (secret)

Only io.github.cyanheads/chembl-mcp-server asks for

  • CANVAS_PROVIDER_TYPE
  • CHEMBL_API_BASE_URL
  • CHEMBL_DATAFRAME_DROP_ENABLED
  • CHEMBL_DEFAULT_LIMIT
  • CHEMBL_MAX_CONCURRENT_PAGES
  • CHEMBL_MAX_PAGE_SIZE
  • CHEMBL_MAX_SPILL_ROWS
  • CHEMBL_REQUEST_TIMEOUT_MS
  • CHEMBL_SPILL_DEADLINE_MS
  • MCP_AUTH_MODE
  • MCP_HTTP_ENDPOINT_PATH
  • MCP_HTTP_HOST
Show the remaining 3
  • MCP_HTTP_PORT
  • MCP_LOG_LEVEL
  • MCP_TRANSPORT_TYPE

Settings as each marketplace publishes them. Asking for fewer is not better in itself.

What it can do: Chroma · What it can do: io.github.cyanheads/chembl-mcp-server · Compare two other plugins

Data comes from the Docker MCP Catalog (desktop.docker.com/mcp/catalog) and Docker Hub. Data comes from the Official MCP Registry (registry.modelcontextprotocol.io), CC0 1.0. Figures come from our own regular passes over the marketplaces, last read on . We publish no contact details for plugin publishers.

Where the data comes from: how the catalog is built