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io.github.cyanheads/uniprot-mcp-server

Protein research over UniProtKB: search by function, fetch curated records, map IDs, proteomes.

MCP server · by cyanheads

About

io.github.cyanheads/uniprot-mcp-server is an MCP server published by cyanheads. Marketplaces we read that list it: 1 (Official MCP Registry). The last change we recorded was on 2026-10-12. As of our marketplace pass on 2026-10-14.

What it asks for

  • Runs remotely
  • Settings: 6

What it declares, asks for and runs, in full

Only install plugins from developers you trust. We list what marketplaces publish and do not test plugins.

Package

npm @cyanheads/uniprot-mcp-server (@cyanheads/uniprot-mcp-server on npm)

  • npm downloads/week: 308 (2026-10-12)
  • npm downloads/month: 778 (2026-10-12)
  • Latest version on npm: 0.2.5, published 2026-10-09
  • Declared version 0.2.6 is not listed on npm

npm facts come from the public npm registry (registry.npmjs.org, api.npmjs.org). Each figure is the registry's own and is never added to another. A registry that publishes no figure shows none: no number is not zero.

Works with

  • Claude Code
  • Codex
  • Cursor
  • VS Code
  • Copilot CLI

A one-click link opens the client, which asks you to confirm before it adds the server.

From the marketplaces that list it and the MCP transport it declares, as each client documents them. We do not test plugins.

Observed by Ext Ops

Observed by Ext Ops on 2026-10-14: what the endpoint itself answered when asked to list its tools. We never call the tools.

Tools: 6 · Resources: 0 · Prompts: 1

Server: uniprot-mcp-server 0.2.6 · MCP protocol version 2025-06-18

Tool metadata as listed on 2026-10-14: annotations on 6 of 6 tools · parameter descriptions on 31 of 31.

  • uniprot_get_entryFetch full curated UniProtKB entries by accession in one batch (up to 20). Each entry carries function, catalytic activity, cofactors, subcellular location, disease involvement, PTMs, natural variant…
  • uniprot_get_proteomeFetch the reference proteome for an organism by UPID (e.g. "UP000005640") or NCBI taxon ID (e.g. 9606) — provide exactly one. Returns metadata inline: proteome type, total protein count, BUSCO comple…
  • uniprot_get_sequenceFetch the canonical amino-acid sequence (FASTA) for a UniProtKB accession, with length and the parsed header. Set include_isoforms to also return the alternatively-spliced isoform sequences. This is…
  • uniprot_get_taxonomyResolve a taxonomy record by NCBI taxon ID (e.g. 9606) or scientific name (e.g. "Homo sapiens") — provide exactly one. Returns the scientific and common name, mnemonic, rank, parent, and the full lin…
  • uniprot_map_idsTranslate identifiers across databases via UniProt's ID-mapping service — gene names to accessions, accession to PDB / Ensembl / RefSeq / ChEMBL / GeneID, and back. The job runs asynchronously; this…
  • uniprot_search_proteinsSearch UniProtKB and return curated protein records. Pass text_search for a plain-language query (the 80% case) or query for the full Lucene field syntax (gene:TP53 AND organism_id:9606 AND reviewed:…

Its marketplaces publish no list of tools.

How we check endpoints

Connect

Commands and configs built only from what its marketplaces declare. We do not run them for you and do not test plugins.

As a remote MCP server

Built from what Official MCP Registry declares.

Claude CodeTerminal
claude mcp add --transport http uniprot-mcp-server https://uniprot.caseyjhand.com/mcp
Codex~/.codex/config.toml
[mcp_servers.uniprot-mcp-server]
url = "https://uniprot.caseyjhand.com/mcp"
Cursor~/.cursor/mcp.json
{
  "mcpServers": {
    "uniprot-mcp-server": {
      "url": "https://uniprot.caseyjhand.com/mcp"
    }
  }
}

Where it is published

MarketplaceStatusVersionFiguresVerifiedFirst seen
Official MCP Registry (Open the registry record) Listed 0.2.6 Downloads/month (npm): 778
Downloads/week (npm): 308
Forks (GitHub): 0
Stars (GitHub): 2
Not marked

Each figure is the marketplace's own and is never added up across marketplaces. A marketplace that publishes no figure shows none: no number is not zero.

What changed

  1. Official MCP Registry: released version 0.2.6 (was 0.2.5)

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Found by meaning, not by shared code or a shared repository: similar plugins stay separate products, and this is not a review or a recommendation.

Is this your plugin?

Add it to your projects and prove you maintain it with a file in its repository, a file on your domain or a DNS record. You get alerts when a marketplace lists it, drops it, changes its verified mark or what it asks for, and its remote endpoint goes on monitoring as a web service.

Data comes from the Official MCP Registry (registry.modelcontextprotocol.io), CC0 1.0. Figures come from our own regular passes over the marketplaces, last read on . We publish no contact details for plugin publishers.

Where the data comes from: how the catalog is built