io.github.cyanheads/interpro-mcp-server

Name: io.github.cyanheads/interpro-mcp-server
Author: cyanheads

Search InterPro entries, map domains onto proteins and PDB structures, and scan raw sequences.

MCP server · by cyanheads

Connect Compare Claim

About

io.github.cyanheads/interpro-mcp-server is an MCP server published by cyanheads. Marketplaces we read that list it: 1 (Official MCP Registry). The last change we recorded was on 2026-10-28. As of our marketplace pass on 2026-11-06.

What it asks for

Runs remotely
Settings: 7

What it declares, asks for and runs, in full

Only install plugins from developers you trust. We list what marketplaces publish and do not test plugins.

Package

npm @cyanheads/interpro-mcp-server (@cyanheads/interpro-mcp-server on npm)

npm downloads/week: 0 (2026-11-02)
npm downloads/month: 0 (2026-11-02)
Latest version on npm: 0.2.0, published 2026-10-28

npm facts come from the public npm registry (registry.npmjs.org, api.npmjs.org). Each figure is the registry's own and is never added to another. A registry that publishes no figure shows none: no number is not zero.

Works with

Claude Code
Codex
Cursor
VS Code
Copilot CLI

Install in Cursor Install in VS Code

A one-click link opens the client, which asks you to confirm before it adds the server.

From the marketplaces that list it and the MCP transport it declares, as each client documents them. We do not test plugins.

Observed by Ext Ops

Observed by Ext Ops on 2026-11-06: what the endpoint itself answered when asked to list its tools. We never call the tools.

Tools: 9 · Resources: 1 · Prompts: 0

Server: interpro-mcp-server 0.2.0 · MCP protocol version 2025-06-18

Tool metadata as listed on 2026-11-06: annotations on 9 of 9 tools · parameter descriptions on 45 of 45.

interpro_find_proteins_by_domainFind UniProt proteins carrying an InterPro or member signature. Defaults to reviewed human proteins; reviewedOnly=false includes all review statuses in the chosen taxon. Optional isFragment filters f…
interpro_get_clanRetrieve a Pfam, CDD, or PIRSF clan/set and a cursor page of member entries; optionally include its relationship graph, returned in slices that fit the response budget and paged with relationshipOffs…
interpro_get_entryRetrieve one InterPro or member-database entry with full metadata by default. Select optional sections while retaining core and unknown metadata, or supply overlapLimit to page whole overlap records…
interpro_get_protein_domainsRetrieve InterPro and member-signature matches on a canonical UniProt protein, preserving every location and discontinuous fragment. Optionally select records covering a residue, include extra predic…
interpro_get_scan_resultCheck an InterProScan job started by interpro_scan_sequence, waiting up to waitSeconds for it to finish. Returns the matches once finished, otherwise its queued or running status to check again later…
interpro_get_structure_domainsRetrieve InterPro and member-signature matches on one PDB entry's protein chains. Each chain record keeps match locations in chain numbering (1-based start/end beside author auth_start/auth_end, whic…
interpro_list_referenceList supported InterPro database slugs, entry types, accession and PDB identifier patterns, common taxon IDs, or current release information.
interpro_scan_sequenceFind InterPro domain, family, and site matches for one raw protein sequence that has no UniProt accession. Sequences already in UniParc return precalculated matches at once; any other sequence starts…
interpro_search_entriesSearch InterPro entries or member signatures by text or entry type. GO filters require sourceDatabase interpro; integratedInto selects member signatures for an InterPro accession. Results are cursor-…

Its marketplaces publish no list of tools.

How we check endpoints

Connect

Commands and configs built only from what its marketplaces declare. We do not run them for you and do not test plugins.

As a remote MCP server

Built from what Official MCP Registry declares.

Claude CodeTerminal

claude mcp add --transport http interpro-mcp-server https://interpro.caseyjhand.com/mcp

Codex~/.codex/config.toml

[mcp_servers.interpro-mcp-server]
url = "https://interpro.caseyjhand.com/mcp"

Cursor~/.cursor/mcp.json

{
  "mcpServers": {
    "interpro-mcp-server": {
      "url": "https://interpro.caseyjhand.com/mcp"
    }
  }
}

Where it is published

Marketplace	Status	Version	Figures	Verified	First seen
Official MCP Registry (Open the registry record)	Listed	0.2.0	Downloads/month (npm): 0 Downloads/week (npm): 0 Forks (GitHub): 0 Stars (GitHub): 1	Not marked	2026-10-21

Each figure is the marketplace's own and is never added up across marketplaces. A marketplace that publishes no figure shows none: no number is not zero.

How its figures have moved

Stars (GitHub)

unchanged since 22.10

1 · 2 readings

2026-10-221
2026-11-061

Each dot is a day we read a different number; flat stretches are days the number did not move. Figures of different marketplaces are never added up.

What changed

2026-10-28Official MCP Registry: description changed
2026-10-28Official MCP Registry: environment variables changed (now 7): added INTERPRO_SCAN_EMAIL
2026-10-28Official MCP Registry: released version 0.2.0 (was 0.1.3)
2026-10-24Official MCP Registry: released version 0.1.3 (was 0.1.2)
2026-10-24Official MCP Registry: moved from running on your machine to a remote server
2026-10-24Official MCP Registry: released version 0.1.2 (was 0.1.1)
2026-10-21Became a product we track
2026-10-21Official MCP Registry: appeared

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Data comes from the Official MCP Registry (registry.modelcontextprotocol.io), CC0 1.0. Figures come from our own regular passes over the marketplaces, last read on 2026-11-06. We publish no contact details for plugin publishers.